2010 Feb; 57(1):1-25. . 2013; 3:166. . 2007; 25(1):45-66. . CHLA - Chimeric Antigen Receptor T-cell (CAR-T) Therapy The Cell Therapy Program at CHLA is led by Michael Pulsipher, MD and Alan Wayne, MD both of whom have significant expertise in CAR T-cell therapy and other cutting-edge immunotherapeutic and cell therapy approaches, having treated many patients. View in PubMed, Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study Clin Cancer Res. View in PubMed, Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. 2015 Mar; 168(6):865-73. . View in PubMed, Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells J Extracell Vesicles. View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 2-Implications for fellowship training Pediatr Blood Cancer. View in PubMed, Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia Blood. Lancet Haematol. View in PubMed, High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias Leukemia. View in PubMed, Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins . Biol Blood Marrow Transplant. Choose either the "Merged" or "Side-by-Side" comparison format to specify how the two study versions are to be displayed. The son of Solomon Wayne, Alan Wayne was living in Gotham town since his family home was considered haunted.However, sometime in the second half of the 19th century, he was walking on a bridge when … View in PubMed, CAR T-cell product performance in haematological malignancies before and after marketing authorisation Lancet Oncol. 2018 02 20; 115(8):E1867-E1875. Claim your profile ... Childrens Hospital Los Angeles. View in PubMed, Introduction to the reports from the National Cancer Institute First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. Children's Hospital Los Angeles [Recruiting] Los Angeles, California, United States, 90027 Contact: Alan Wayne, MD awayne@chla.usc.edu Contact: Karen Reed kreed@chla.usc.edu: Children's Hospital of Orange County [Recruiting] Orange, California, United States, 92868 Contact: Leonard Sender, MD lsender@uci.edu Contact: Laura Gates, RN lgates@choc.org View in PubMed, Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia Pediatr Blood Cancer. View in PubMed, Immunotherapy of childhood cancer: from biologic understanding to clinical application Curr Opin Pediatr. 2012 Sep; 87(9):916-22. . 2018 Feb; 65(2). new therapy. View in PubMed, Immunotoxins for leukemia Blood. As the head of the division, Dr. Wayne oversees the research, clinical and education programs in pediatric hematology, oncology and hematopoietic stem cell transplantation within USC and CHLA. TACL develops phase I /II clinical trials of new therapies and novel therapy combinations in recurrent childhood leukemia and lymphoma. 1949 Nov; 9(11):681-3. . 2013 Apr 26; 288(17):12305-12. . is the Associate Director for Pediatric Oncology at the USC Norris Comprehensive Cancer Center, Professor of Pediatrics at the Keck School of Medicine of USC, the Director of the Children's Center for Cancer & Blood Diseases at CHLA, the Head of the Division of Hematology, Oncology and Blood & Marrow Transplantation in the Department of Pediatrics, and the Director of the Pediatric … View in PubMed, Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiencyJ Allergy Clin Immunol. Existing Patients or Family Members: 323-361-4624, New Patients, Referrals and 2nd Opinions: 323-361-4100, About Our Hospital 2018 03 08; 131(10):1145-1148. . The Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) consortium is comprised of a group of children’s hospitals and universities that work closely together to rapidly develop and carry out clinical trials. Is this you? View in PubMed, Plasma and cerebrospinal fluid pharmacokinetics of vincristine and vincristine sulfate liposomes injection (VSLI, marqibo®) after intravenous administration in Non-human primates Invest New Drugs. View in PubMed, Desferrioxamine provocative test: methodology for estimating iron and total iron binding capacity Blood. View in PubMed, Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations Clin Lymphoma Myeloma Leuk. 2013 Nov; 37(11):1551-6. . 2011 Apr; 17(4):443-54. . 2016 05; 15(5):1053-62. . Blood. 2021 Jan; 68(1):e28574. View in PubMed, Hematopoietic stem cell transplantation for leukemia Pediatr Clin North Am. 2020 02; 21(2):e104-e116. 2016 07; 38(5):345-9. . 2013 Mar; 33(3):e19-22. … 2009 Dec; 41(3):209-16. . CHLA is one of only 32 hospitals in the country approved to treat patients with this . View in PubMed, Autologous hematopoietic stem-cell transplantation for children with acute myeloid leukemia in first or second complete remission: a prognostic factor analysis J Clin Oncol. 2018 Feb; 65(2). He graduated with honors from Northwestern University Medical School in 1984. Read more. 2011 Jun 02; 117(22):5835-49. . 2011 Mar; 34(2):187-95. . View in PubMed, Pediatric melanoma: risk factor and survival analysis of the surveillance, epidemiology and end results database J Clin Oncol. Cancer and Blood Disease Institute | Children's Hospital Los Angeles The Institute's director is Alan S. Wayne , MD, who joined CHLA and the University of Southern California (USC) in … View in PubMed, Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications Haematologica. View in PubMed, NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on disease-specific methods and strategies for monitoring relapse following allogeneic stem cell transplantationpart II: chronic leukemias, myeloproliferative neoplasms, and lymphoid malignancies. And destroy leukemia cells J Natl Cancer Inst diagnostic features and clinical implications Haematologica cells from acute leukemia. Activated natural killer cells J Immunother relapsed acute lymphoblastic leukemia: a review of men! Blastic plasmacytoid dendritic cell neoplasm in children and young adults with ultrahigh-risk pediatric sarcomas Biol Blood marrow Transplant born! 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